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Author Topic: Plants Which are BOTH Nutritional and Medicinal  (Read 5074 times)

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AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #45 on: April 10, 2018, 06:28:45 pm »

 :) Hey Surly and RE,

My wife discovered a great (real 😋) banana 🍌 treat from Vitacost. It's a way to get all that good potassium from bananas without frequent trips to the grocery store. They aren't cheap, but I think they are worth it.

This guy in Brazil started dehydrating bananas that were blemished or too ripe for marketing some decades ago. Vitacost sells them now. They taste great and have the same nutritive value as fresh bananas due to the clever dehydration process (partial, they can be chewed and are not rock hard like other dehydrated products out there - to prevent further ripening, even though dehydration is partial, they use some banana dust over the bite sized portions).

😋

This is a great way to make use of food that would have been thrown out previously due to the ridiculous fruit marketing practices that force markets to only sell fruit with no blemishes. Also, this guarantees a higher marketable yield (and profit  :icon_mrgreen:) for growers, as well as saving a lot of energy, because these products require no refrigeration whatsoever.

RE could stock up on these to guarantee he has enough potassium if he is homebound due to health problems. We all need potassium. Without enough, we begin to feel fatigued and listless. We can lose muscle tone from lack of potassium. This is not limited to our large muscles. Lack of K can adversly affect peristaltic esophageal movement needed to send food down to the stomach and also intestinal movement needed for proper digestion.

Potassium: 10 Symptoms of Potassium Deficiency 🚩

By: Dr. Helen Okoye, MD on 28 Mar, 2018

SNIPPET:

Potassium Deficiency Symptom #1: Muscle Weakness

Muscle weakness is the most common symptom associated with a potassium deficiency. Potassium plays a key role in promoting muscle strength and the overall wellbeing of muscle tissue. The muscle weakness can make it more difficult for an affected person to properly move their legs and arms.

Potassium Deficiency Symptom #2: Muscle Cramps
In addition to muscle weakness, many individuals who suffer from a lack of potassium in their body also experience muscle cramps. Muscle cramps may be mild or severe, and can affect a number of different muscle groups in the body.

full article:

http://10faq.com/health/potassium-deficiency-symptoms/

NOTE:
There are other foods out there besides bananas that have more potassium, but I like the taste of bananas.  ;D

13 Foods That Have More Potassium Than a Banana
FoodNutritionPublished on Tuesday, October 24th, 2017 @ 7:59 pm

Health Team

By Trista

SNIPPET:

If you need potassium, your go-to source is usually bananas. Peel a medium one and you will get about 422 milligrams of potassium, which is around nine percent of your 4,700 milligrams recommended daily intake. Well, what if you don’t like bananas, or just want something new? There are a plethora of foods that can give you potassium and other essential vitamins and minerals. In fact, some of them might surprise you! Check out these 13 foods that have more potassium than a banana.

Full article:

http://health.facty.com/food/nutrition/13-foods-that-have-more-potassium-than-a-banana/





Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #46 on: April 10, 2018, 08:21:53 pm »
Quote

Hey Surly and RE,  My wife discovered a great (real 😋) banana 🍌 treat from Vitacost. It's a way to get all that good potassium from bananas without frequent trips to the grocery store. They aren't cheap, but I think they are worth it.

Another good example of hw you can learn something new every day around here. I had no idea.

Thanks, AG.


Glad to be of service.   


Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #47 on: July 17, 2018, 07:11:12 pm »
What Effect Does Catnip Have On Humans?
By: Tracy Hall

Have you ever watched a cat playing with a catnip toy and wondered what the experience was like? An estimated 70-90% of domestic cats have some reaction to this member of the mint family, and it's hard not to be curious. After all, who wouldn't want to share in the giddy frenzy or blissful relaxation of a playtime session with their feline friend? Throughout history many cultures have experimented with Nepeta cataria, commonly known as catnip, the extent of which might surprise you.

For felines, the main attractant in catnip is a chemical called nepetalactone. This oil is metabolized in the cat's body and passes harmlessly through urine. How humans discovered the effect that the herb had on animals is unclear. It is also unclear when humans began using it for themselves. However, there are countless records of humans using catnip for medicinal purposes. Its use in the treatment of illnesses was prominent enough for catnip to be included in the United States Pharmacopeia from 1840-1890. Catnip has been used to treat nervousness, menstrual cramps, digestive tract irritation, colds, and the flu. It was only a matter of time before curiosity got the best of people and they decided to explore even more applications. Eventually there surfaced yet another potential use of catnip: as an intoxicant.

The intoxicating effect of catnip has long since been the stuff of urban legends. According to one paper on catnip, it was used as a "filler" in (or even in place of) marijuana in the 1960's. Today, an Internet search for "catnip human intoxicant" yields more than 10,000 results. Despite this number, the vast majority of published experiences have come from individuals, not research groups. Most indicate the ingestion of catnip via drinking tea or smoking, either by itself or mixed with tobacco. And the effects are...reportedly, nothing like Fluffy's.

Most people indicate mild feelings of relaxation or drowsiness, coupled with complaints of foul taste or smell. At higher doses, some users feel nauseous. Some have suggested that the lightheaded feeling sometimes caused by smoking catnip is due to simple lack of oxygen in the body. Notably lacking are the euphoric or hallucinogenic experiences suggested by feline reactions to the herb.

In short, catnip has a long history of human use and is still included today in many natural remedy compendiums. Although it might help quell a stomachache or calm frazzled nerves, humans experience few, if any, intoxicating effects from catnip. So when it comes to "feelin' groovy", it's best to leave the toy mice to the cats.

Resources:

http://www.herbcompanion.com/herb-profiles/herb-basics-catnip-not-just-for-felines-anymore.aspx
http://jama.ama-assn.org/cgi/content/summary/208/7/1190-a
http://www.springerlink.com/content/f613756573257t02/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1480656/?page=2

Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #48 on: July 17, 2018, 07:28:02 pm »
7 Herbs that Grow in Shade

By Leda Meredith

Wondering what to plant in those shady areas of your landscape? There’s no need to resign yourself to standard shade-fillers, like pachysandra and ivy, when you could be growing useful herbs that thrive in low-light conditions. While many culinary herbs do require lots of direct sunlight (like basil and oregano, which originated in the sunny Mediterranean), other herbs usually listed as full-sun plants will do just fine in partial shade. Parsley, anise hyssop, lemon balm and shiso are among the best herbs for dappled light or areas that receive only a couple of hours of direct sun daily.

Other, less-familiar herbs actually prefer shade. In nature, these plants can be found growing in the dappled light below trees, or at the edges of forests, where the sun shines directly on them for only a short time each day. These plants—which include wild ginger, spicebush and sweet woodruff—will do beautifully in a shady garden site, and will add enticing new flavors and aromas to your cooking.

For beds and borders shaded by trees, fences or buildings, try one or more of these seven stars for shade.

1. Sweet woodruff

Sweet woodruff (Galium odoratum; Zones 5-8).


A wonderful groundcover, this European native bears lacy, white flowers in late spring. A naturally moist or irrigated site is best. Both leaves and flowers have a fresh scent and make a delicately sweet tea. In Germany, the flowering tops are traditionally used to make May wine. To make your own May wine, steep flowers in Riesling wine overnight, strain out the woodruff, and add strawberries. Serve chilled.

Avoid consuming sweet woodruff if you have circulatory problems or if you are pregnant


2. Anise hyssop
Anise hyssop (Agastache foeniculum; Zones 4-10).

Many culinary and medicinal herbs thrive in partial or full shade. Although gardening guides continue to list anise hyssop (shown this page) as suitable for “full sun only,” this native American perennial will bloom and thrive in partial shade. Both the flowers and leaves have an intense licorice aroma and flavor. Fresh or dried, the herb makes a delicious tea that pairs well with baked goods like scones, muffins and biscotti. Dried anise hyssop leaves also can be used in place of anise seeds to flavor cookies.

Anise hyssop has a long history of medicinal use by Native Americans. The Cheyenne used anise hyssop tea to relieve depression, while the Cree and Chippewa included it in protective medicine bundles.

3. Wild ginger

Wild ginger (Asarum canadense; Zones 2-8) is native to the woodlands of North America. An attractive groundcover with heart-shaped leaves, wild ginger also can be used to flavor both sweet and savory dishes. To harvest wild ginger without destroying the perennial, dig about 2 inches into the soil between the plants. Snip off a few inches of the rhizomes, then pat down the soil. You can harvest in this fashion several times a year without decimating your beautiful patch of wild ginger.

4. Parsley

Parsley (Petroselinum spp.; Zones 5-9).

This Mediterranean biennial has been cultivated since at least the 3rd century b.c. Choose flat-leaf parsley (Petroselinum crispum var. neapolitanum; shown at right) for flavor and curly parsley (P. crispum) for garnishes. In addition to using the leaves in almost any savory dish, you can use the chopped roots—which taste like a cross between parsnips and carrots—in soups and stews.

The plant is quite cold-hardy and can be harvested even when temperatures hover around freezing.

5. Shiso

Shiso (Perilla frutescens; annual), also called beefsteak plant, has three leaf color variations (purple, green and a bicolor), all of which are as ornamental as they are tasty. Shiso self-seeds readily in the garden, but because of its shallow root system, it’s easy to weed out.

In Japan, purple shiso (shown above) is used to color the pickled ginger served with sashimi. Shiso’s versatile flavor, a combination of cilantro and mint with spicy overtones, is as good with fresh fruit as it is with savory seafood and rice dishes.

Shiso Salad

Serves 4
• 2 cucumbers, peeled and sliced
• 2 tablespoons seasoned rice vinegar
• 1 large peach, peeled and chopped
• ¼ cup green or purple shiso, chopped
• Pinch of salt
1. Combine cucumbers and vinegar; let stand at room temperature 10 minutes.

2. Add peach, shiso and salt. Toss to combine.

6. Lemon balm

Lemon balm (Melissa officinalis; Zones 3-7) is a European perennial that does as well in shade as it does in full sun. Its delightful lemon scent comes from its high essential oil content. The leaves are best harvested in mid-spring. As a culinary herb, lemon balm makes a delicious tea and the minced leaves are a nice addition to fruit salads. Essential oil of lemon balm is used in aromatherapy as an antidepressant. The herb loses its potency when dried, but the fresh herb can be tinctured to preserve its medicinal properties.

In the garden, lemon balm can be invasive. Prune off the flowering tops before they go to seed.

Lemon Balm Butter Sauce

Serves 4 to 6
• 2 tablespoons fresh lemon balm leaves, minced
• 1⁄4 cup butter, melted
• Salt, to taste
1. Add lemon balm to melted butter.

2. Wait 30 seconds, then toss with cooked vegetables.

7. Spicebush
Spicebush (Lindera benzoin; Zones 4-9), sometimes called northern spicebush, is a lovely, native American woodland shrub that thrives in partial shade, such as it would have at the edge of a forest clearing. Spicebush grows to 10 feet tall, with pretty, teardrop-shaped leaves 2 to 5 inches long.

The entire plant is aromatic. The female plants produce fragrant yellow flowers in early spring, followed by small, bright-red oval fruit in autumn. (Because spicebush is dioecious, both male and female plants are needed for fruit production; check with your supplier to be sure you are getting both if you wish to obtain the berries.)

Use the fresh leaves in hot or iced tea; they do not retain their flavor well when dried. The twigs can be simmered in water for a warming tea any time of year.

In the fall, collect the red berries and dry them to use as a spice that has both sweet and savory uses. Sometimes sold as “Appalachian allspice,” spicebush can be used like allspice and makes a scrumptious ice cream and spice cake. The berries have a peppery note that makes them an excellent addition to meat rubs and marinades, as well.

The Ojibwa and Iroquois tribes treated spicebush berries as two different seasonings. They separated the seeds from the surrounding pulp and red skins. The pulp and skins were used for their sweet, allspice-like taste and the seeds for their peppery bite. If you want to separate the berries into two different spices, do so before drying or freezing as they are almost impossible to separate after preserving. Separated or whole, the berries have a high fatty oil content and can go rancid if stored at room temperature. Store both fresh and dried spicebush in the freezer. To use, grind in an electric coffee grinder. Note: Take care not to confuse Lindera benzoin with another native American shrub, Calycanthus floridus, commonly called “Carolina allspice” and also sometimes called “spicebush.”

Calycanthus floridus

To Buy: Spicebush, sweet woodruff and wild ginger are available from Forestfarm, (541) 846-7269, www.forestfarm.com; Lazy S’S Farm Nursery, www.lazyssfarm.com; and Companion Plants, (740) 592-4643, www.companionplants.com. Anise hyssop, lemon balm, parsley and shiso are widely available; mail-order suppliers include Companion Plants; Johnny’s Selected Seeds, (877) 564-6697, www.johnnyseeds.com; and Richters, (905) 640-6677, www.richters.com.

Leda Meredith is a botanist, writer and instructor at the New York Botanical Garden and the Brooklyn Botanic Garden, specializing in edible and medicinal plants. She is the author of Botany, Ballet, & Dinner from Scratch: A Memoir with Recipes (Heliotrope Books, 2008).

Source: http://www.motherearthliving.com/
Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #49 on: August 12, 2018, 12:44:35 pm »

Red Clover Herb

Eating clover

The leaves, flowers, seeds, and roots of clovers are all edible.
😋

The young leaves, taken before the plant flowers, can be eaten raw in salads. As the plant matures, cooking the leaves is recommended. The dried leaves are said to add a slightly vanilla-like flavor to baked goods. In my own experience with clover leaves, I found them to be rather bitter (maybe I picked them at the wrong time). I stick to the flowers.

The roots should be eaten cooked.

The flowers and seeds are the parts of the clover that are of greatest interest to most foragers. The flowers are used raw in salads as well as sauteed, stir-fried, or fried as fritters. They are also popular for making teas and wines.

The flowers and seeds can be dried and ground into a flour.

The binomial name for white clover is Trifolium repens. Red clover is Trifolium pratense.

All of those are Latin words. Trifolium means "three leaves", repens means "recent, sudden, or fresh", and pratense means "found in meadows."

The clovers are native to Europe, Asia, and northern Africa. They were introduced to the Americas by settlers. Clover is commonly used as fodder for livestock and is also a valuable soil builder.

http://www.squidoo.com/trifolium

Agelbert NOTE: When I was a kid in Kansas, I used to eat clover leaves and stems by the bunches. They have a nice sour pickly taste. I never did eat the flowers though. I figured if bees liked them, some small bugs might like them too and I would eat them by mistake. Bugs never were my thing.  :P :D
Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #50 on: October 19, 2018, 05:16:22 pm »
Trump 🦀 AG Cracker Sessions 🐵 Keeps Doing STUPID on Behalf of the Racist U.S. Prison Industrial Complex. 

As Canada Legalizes Marijuana the US 🦍 Tightens Border Controls

October 18, 2018

Canada, the US’s largest trading partner legalized marijuana. Most states bordering Canada it is legalized or medicalized. However, the Trump administration plans to deny entry to Canadians who use or sell marijuana


https://therealnews.com/stories/as-canada-legalizes-marijuana-the-us-tightens-border-controls
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AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #51 on: June 01, 2019, 06:44:56 pm »

Where Is Most of the World’s Olive Oil Produced?

Olive trees have grown in the countries surrounding the Mediterranean Sea since the 8th millennium BC. The hardy trees have robust root systems and can live as long as 2,000 years. The oil from olives is actually this fruit’s juice, and is typically used in cooking or as a salad dressing. It is also incorporated into soaps and pharmaceuticals (to reduce high blood pressure), and as an additive in cosmetics (particularly skin cream). Spain is, by far, the world's largest producer of olive oil, especially in southern parts of the country. According to statistics from the International Olive Council, Spain's virgin olive oil output during the 2016-2017 period was nearly twice that of Italy, Greece, and Tunisia combined.

The awesome olive:

֍ While Spain produces the most olive oil, Greece consume more of it than any other country. In fact, the average Greek consumes about 5.3 gallons (20 liters) of olive oil a year.

֍ The entire olive is crushed during processing; they are typically harvested twice a year. An early harvest begins in October, and those oils are particularly high in antioxidants and polyphenols. The main harvest occurs in November and December.

֍ Olives are still hand-picked, although some harvesters use mechanical means to shake the tree’s branches, causing olives to fall into nets. Each tree can produce about 66 lbs (30 kg) of fruit, or one gallon (4 liters) of oil.

https://www.wisegeek.com/where-is-most-of-the-worlds-olive-oil-produced.htm
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AGelbert

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Marijuana Policy Project

Major victory: House votes to protect legal marijuana states from 🦀 DOJ interference

On June 21, an extraordinary milestone was achieved in the U.S. House of Representatives when the body approved a measure by a 267-165 vote to prevent the Department of Justice from using funds to interfere with the implementation of state laws that have legalized marijuana for adults.

Read more:
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AGelbert

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Cannabis provides strong pain relief

Analysis by Dr. Joseph Mercola Fact Checked

August 05, 2019
 
STORY AT-A-GLANCE

Clinical findings from researchers in Canada indicate that the pain-relieving effects of the cannabis plant are 30 times more potent than aspirin for decreasing inflammation

Besides the psychoactive aspects of tetrahydrocannabinol (THC) and the pharmacological features of cannabinoids, such as cannabidiol (CBD) derived from C. sativa varieties, there’s potential for other medicinal uses

To explore the “medicinal versatility” of cannabis, scientists focused on two specific molecules, cannflavin A and cannflavin B, to identify the biosynthesis that made them “medicinally relevant”

Experts say the breakdown between marijuana and hemp is fairly simple: When a cannabis plant contains 0.3% or less of THC, it’s hemp; when it contains more than 0.3% of THC, it’s marijuana

Low doses of CBD administered for seven days were found to alleviate pain and anxiety, symptoms often associated in neuropathic or chronic pain, but without the side effects or potential of addiction from opioids

Full article:

https://articles.mercola.com/sites/articles/archive/2019/08/05/cannabis-provides-strong-pain-relief.aspx
Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

AGelbert

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Re: Plants Which are BOTH Nutritional and Medicinal
« Reply #54 on: September 15, 2019, 05:20:56 pm »
EcoWatch

Quote
Though scientists have primarily focused on coffee when researching the positive effects of caffeine, both drinks — despite containing differing amounts of this substance — can provide its associated health benefits.

Healthline Sep. 08, 2019 09:41AM EST

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AGelbert

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Ashitaba Plant

September 16, 2019

Ashitaba — A Most Powerful yet Unknown Herb

Analysis by Dr. Joseph Mercola Fact Checked

Native to Japan, ashitaba (Angelica keiskei koidzumi1) is a bitter leafy herb of the Angelica genus, closely related to the carrot. It's also known as "tomorrow's leaf," due to its rapid growth and regenerative abilities. It's a fast grower and new leaves rapidly sprout when picked.

The plant is well-known in China and Japan, having been part of the diet since ancient times. There, it has also been used medicinally for hundreds of years, as a general health promoter and antiaging remedy.2

The first reference to ashitaba is found in the Chinese Compendium of Materia Medica, compiled by Li Shizhen, a famous acupuncture physician and pharmacologist, between 1552 and 1578.3 According to a 2013 investigation,4 ashitaba "might be a useful agent in preventing deficit of learning and memory caused by AD [Alzheimer's disease] and aging."


STORY AT-A-GLANCE

֍ Native to Japan, ashitaba (Angelica keiskei koidzumi) is a bitter leafy herb of the Angelica genus, closely related to the carrot. It’s also known as "tomorrow's leaf," due to its rapid growth and regenerative abilities

֍ In China and Japan, ashitaba has been used medicinally for hundreds of years as a general health promoter and antiaging remedy

֍ Recent research shows ashitaba is a potent inducer of autophagy, capable of increasing the life span of nematodes and fruit flies by 20%

֍ The flavonoid responsible for ashitaba’s antiaging effects is 4,4′-dimethoxychalcone (DMC). Of 180 plant flavonoids screened using three different assays, DMC offered the strongest cellular protection

֍ DMC was also found to protect against liver damage caused by excess alcohol consumption in animals, and inhibited the proliferation of certain human cancer cells

Full article:

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AGelbert

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RECENT META-ANALYSIS RESULTS
CAN ASPIRIN REDUCE YOUR RISKS OF CANCER?   

ASPIRIN 🎍 META-ANALYSIS IS DISCUSSED

Learn how a recent meta-analysis regarding consuming low daily doses of aspirin found in certain🎍 foods look promising for your health.   


Studies show that taking low doses of aspirin daily may result in a decreased chance of developing cancer in your future.

These results may have a remarkable impact on the future health of society.

THE BRASSCHECK/REAL FOOD READING LIST
We recommend these books as a foundation for educating yourself about health in the 21st Century.

https://realfoodchannel.com/recent-meta-analysis-results/

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AGelbert

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Dietary naturally occurring salicylates
« Reply #57 on: November 05, 2019, 10:00:09 pm »

J Clin Pathol. 2003 Sep; 56(9): 649–650.
doi: 10.1136/jcp.56.9.649
PMCID: PMC1770049
PMID: 12944545

Dietary salicylates 🎍
L G Hare, J V Woodside, and I S Young
Author information Article notes Copyright and License information Disclaimer
This article has been cited by other articles in PMC.


There is overwhelming epidemiological evidence that a high consumption of fruit and vegetables is associated with reduced mortality from cardiovascular disease, cancer, and other causes.1–5 In part, this may simply indicate that high fruit and vegetable consumption is a marker of a healthy lifestyle, but there is also strong evidence from in vitro studies and clinical trials that micronutrients and other components of fruit and vegetables have beneficial biological effects.6–8 Most attention has focused on antioxidants, B group vitamins, minerals, and fibre, but several strands of evidence now indicate that increased intake of salicylates may be another benefit of fruit and vegetable consumption.

In this issue of the journal, Lawrence and colleagues show that urinary excretion of salicyluric acid (SU) and salicylic acid (SA) is significantly increased in vegetarians compared with non-vegetarians.9 They previously reported that serum SA was also significantly increased in vegetarians compared with non-vegetarians.10 Interestingly, urinary excretion of SA was similar in vegetarians and patients consuming 75 or 150 mg of aspirin/day, although SU excretion was substantially greater in the aspirin groups.

“There is strong evidence from in vitro studies and clinical trials that micronutrients and other components of fruit and vegetables have beneficial biological effects”

After oral administration, aspirin (acetylsalicylic acid) is rapidly absorbed in the upper gastrointestinal tract.11 This drug follows first order kinetics and has an absorption half life of five to 16 minutes.12 Aspirin is mainly absorbed unchanged from the lumen of the gastrointestinal tract, but is rapidly hydrolysed to salicylate by carboxylesterases in the gut wall and liver, so that only 68% of the dose reaches the systemic circulation as acetylsalicylic acid.12,13 Salicylate and acetylsalicylate are extensively bound to serum albumin (∼ 50–80%) and are distributed in the synovial cavity, central nervous system, and saliva. The serum half life of acetylsalicylate is 20 minutes, and the decrease in concentration after this time is parallelled by a concurrent rise in salicylate concentrations,12 the half life of which is between two and 30 hours, depending on concentration. SA is metabolised through glucuronide formation, conjugation with glycine, and oxidation to produce SU, salicyl phenolic glucuronide, salicyl acyl glucuronide, gentisic acid, and gentisuric acid.12,13 The kidney eliminates salicylates. The major urinary metabolites are SU (80%) and salicyl phenolic glucuronide (10%), but SA is also partially excreted unchanged (5%).14

Despite the fact that aspirin has been in routine use for almost a century, there is still no common agreement about its mechanisms of action. Aspirin acts by preventing the conversion of arachidonic acid to the cyclic prostenoids via inhibition of the enzyme cyclooxygenase (COX) through acetylation of an essential serine at its active site.11,15 There are two main COX isoforms, COX-1 and COX-2. COX-1 is constitutively expressed in most cells (including platelets) and, among other functions, is essential for the production of thromboxane A2, which causes platelet aggregation.14 COX-2 is not routinely expressed in cells, but is induced rapidly by inflammatory stimuli and growth factors,11 and is the major isoform responsible for prostaglandin biosynthesis in inflamed tissue. Aspirin acts on both forms but is a less potent inhibitor of COX-2.16 Inhibition of COX-1 is achieved by acetylation of serine 530, which is located close to the active site (tyrosine 385 of COX-1). Acetylation of this serine residue hinders the access of arachidonic acid to the active site. Aspirin inhibits COX-2 by a similar mechanism, but is less potent because the substrate channel of COX-2 is larger and more flexible than that of COX-1.16 Mitchell et al, using a variety of in vitro models, suggested that aspirin inhibition of COX-1 was between 25 and 166 times greater than inhibition of COX-2.17

In contrast to aspirin, salicylic acid has virtually no effect on purified COX-1 and COX-2 at pharmacological concentrations, but inhibits prostaglandin synthesis in intact cells.18 The mechanism by which salicylic acid inhibits COX-2 is the subject of much current debate.11–23 One possibility for which there is experimental evidence is that salicylic acid at therapeutic concentrations may suppress COX-2 gene transcription by inhibiting COX-2 mRNA synthesis and COX-2 promotor activity.16,18 As such, with respect to its role as an anti-inflammatory agent, aspirin could be acting as a prodrug for salicylic acid, which has a much longer half life than aspirin.24

The presence of naturally occurring salicylates in fruits, vegetables, spices, confectionaries, and beverages (both alcoholic and non-alcoholic) has been confirmed by several research groups,25–29 although concentrations determined do not always agree.


Swain et al suggested that a normal mixed diet contains total salicylates in the range of 10 to 200 mg/day,26 although other groups have suggested that this may be an overestimate owing to a lack of analytical specificity.27,28 Janssen et al suggested that intake of dietary salicylates in subjects taking a mixed diet was only in the order of 2 to 4 mg/day, an amount probably too low to affect disease risk.28 However, the work reported here9 and previously10 indicates that dietary salicylate intake may be significant in vegetarians and can produce concentrations of SA that overlap with those seen in subjects taking 75 mg of aspirin/day. Because the anti-inflammatory action of aspirin is probably the result of SA,24 and the concentrations of SA seen in vegetarians have been shown to inhibit COX-2 in vitro,18 it is plausible that dietary salicylates may contribute to the beneficial effects of a vegetarian diet, although it seems unlikely that most people who consume a mixed diet will achieve sufficient dietary intake of salicylates to have a therapeutic effect.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770049/

Agelbert NOTE: As a basis for comparison, I've added a graphic (below) showing foods LOW in Salicylates.

Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

AGelbert

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Salicylates: Friend Or Foe?
« Reply #58 on: November 05, 2019, 10:16:09 pm »


Salicylates: Friend Or Foe?


Are you unsure about the state of salicylates and your health? I have heard a lot of talk about salicylates, where you can find them, and how they can have an impact on your health. That’s why I want to dive deep into salicylates, and the research behind them – to really learn whether they are a friend, or a foe, and in what forms each might apply.

What Are Salicylates?

Salicylates are compounds that we can find in a huge variety of plant foods. In fact, they are only found in plant foods! Salicylates are phenolic compounds that plants make as a form of defense (against pathogens and stress ).

The overall data suggests that salicylates seem to be associated with health benefits. As of late, though, that has also cut the other way – with folks worried that they may be the cause of certain symptoms and side effects, as well.

Let me help walk you through learning more about them, if you want them at all in your system, and how much you might want in order to maintain good health.

Learn more: 

https://drchristianson.com/salicylates-friend-or-foe/
Hope deferred maketh the heart sick: but when the desire cometh, it is a tree of life. Pr. 13:12

 

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